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Poster
Reduction in circulating tumor DNA in relation to radiographic response and tumor PD-L1 expression in a phase 1 study of fetrastobart vedotin (PDL1V; PF-08046054) in patients with non-small cell lung cancer
Saleh R, Nabell L, Fontana E, Steeghs N, Kotecki N, Sàbat P, Dowlati A, Zivi A, Ochsenreither S, Le Tourneau C, Oberoi A, Ouali K, Spreafico A, Gillison M, Guo Y, Yao J, Itani F, Gupta S, Zhang R, Minchom A
Fetrastobart vedotin (Fetra-V) | PF-08046054 | May 31, 2026 | ASCO 2026
C5851001 | NCT05208762
Poster
Adjusted Ideal Body Weight Dosing Reduces Pharmacokinetics Variability of the PD-L1–Targeted Antibody-Drug Conjugate PDL1V (PF-08046054)
Iboi E, Chia YL, Zhang F, Harrold J, Forero-Torres A, Lamba M, Garg A, Stoelli F
Fetrastobart vedotin (Fetra-V) | PF-08046054 | October 21, 2025 | ACoP 2025
C5851001 | NCT05208762
Poster
Encouraging Antitumor Activity of PDL1V (PF-08046054) Monotherapy, an ADC Targeting PD-L1, Correlates with Antigen Expression in Patients with NSCLC
Oliva M, Dowlati A, Desai A, Kotecki N, Saleh R, Sukari A, Burkitt K, Steeghs N, Garralda Cabanas E, Zivi A, Laux D, Gillison M, Patniak A, Minchom A, Ochsenreither S, Ouali K, Le Tourneau C, Gupta S, Zhang R, Fontana E
Fetrastobart vedotin (Fetra-V) | PF-08046054 | October 19, 2025 | ESMO 2025
C5851001 | NCT05208762
Poster
Maura Gillison, Marc Oliva, Chrisophe Le Tourneau, Ramy Saleh, Amita Patnaik, Jonathan W. Riess, Neeltje Steeghs, Justin Call, Afshin Dowlati, Elisa Fontana, Elena Garralda Cabanas, Arjun Oberoi, Nuria Kotecki, Anna Minchom, Sebastian Ochsenreither, Kaissa Ouali, Anna Spreafico, Andrea Zivi, Shivani Gupta, Rong Zhang, Lisle Nabell
Fetrastobart vedotin (Fetra-V) | PF-08046054 | June 2, 2025 | ASCO 2025
C5851001 | NCT05208762
Poster
Interim Results of PDL1V (PF-08046054), a Vedotin-Based ADC Targeting PD-L1, in Patients With NSCLC in a Phase 1 Trial
Fontana E, Desai A, Kotecki N, Sàbat P, Le Tourneau C, Steeghs N, Patnaik A, Riess J, Dowlati A, Call J, Garralda Cabanas E, Gillison M, Minchom A, Ochsenreither S, Ouali K, Spreafico A, Zivi A, Gupta S, Zhang R, Saleh R
Fetrastobart vedotin (Fetra-V) | PF-08046054 | May 30, 2025 | ASCO 2025
C5851001 | NCT05208762
Presentation
Interim Results of a Phase 1 Study of SGN-PDL1V (PF-08046054) in Patients with PDL1-Expressing Solid Tumors
Oliva M, Ochsenreither S, Le Tourneau C, Champiat S, Saleh R, Burkitt K, Nabell L, Steeghs N, Spreafico A, Minchom A, Patniak A, Call J, Fontana E, Kotecki N, Cabanas G, Zivi A, Riess JW, Gupta S, Zhang R, Gillison M
Fetrastobart vedotin (Fetra-V) | PF-08046054 | September 13, 2024 | ESMO 2024
C5851001 | NCT05208762