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Poster
Adjusted Ideal Body Weight Dosing Reduces Pharmacokinetics Variability of the PD-L1–Targeted Antibody-Drug Conjugate PDL1V (PF-08046054)
Iboi E, Chia YL, Zhang F, Harrold J, Forero-Torres A, Lamba M, Garg A, Stoelli F
PDL1V | PD-L1-directed Antibody Drug Conjugate | October 21, 2025 | ACoP 2025
C5851001 | NCT05208762
Poster
Encouraging Antitumor Activity of PDL1V (PF-08046054) Monotherapy, an ADC Targeting PD-L1, Correlates with Antigen Expression in Patients with NSCLC
Oliva M, Dowlati A, Desai A, Kotecki N, Saleh R, Sukari A, Burkitt K, Steeghs N, Garralda Cabanas E, Zivi A, Laux D, Gillison M, Patniak A, Minchom A, Ochsenreither S, Ouali K, Le Tourneau C, Gupta S, Zhang R, Fontana E
PDL1V | PD-L1-directed Antibody Drug Conjugate | October 19, 2025 | ESMO 2025
C5851001 | NCT05208762
Poster
Maura Gillison, Marc Oliva, Chrisophe Le Tourneau, Ramy Saleh, Amita Patnaik, Jonathan W. Riess, Neeltje Steeghs, Justin Call, Afshin Dowlati, Elisa Fontana, Elena Garralda Cabanas, Arjun Oberoi, Nuria Kotecki, Anna Minchom, Sebastian Ochsenreither, Kaissa Ouali, Anna Spreafico, Andrea Zivi, Shivani Gupta, Rong Zhang, Lisle Nabell
PDL1V | PD-L1-directed Antibody Drug Conjugate | June 2, 2025 | ASCO 2025
C5851001 | NCT05208762
Poster
Interim Results of PDL1V (PF-08046054), a Vedotin-Based ADC Targeting PD-L1, in Patients With NSCLC in a Phase 1 Trial
Fontana E, Desai A, Kotecki N, Sàbat P, Le Tourneau C, Steeghs N, Patnaik A, Riess J, Dowlati A, Call J, Garralda Cabanas E, Gillison M, Minchom A, Ochsenreither S, Ouali K, Spreafico A, Zivi A, Gupta S, Zhang R, Saleh R
PDL1V | PD-L1-directed Antibody Drug Conjugate | May 30, 2025 | ASCO 2025
C5851001 | NCT05208762
Presentation
Interim Results of a Phase 1 Study of SGN-PDL1V (PF-08046054) in Patients with PDL1-Expressing Solid Tumors
Oliva M, Ochsenreither S, Le Tourneau C, Champiat S, Saleh R, Burkitt K, Nabell L, Steeghs N, Spreafico A, Minchom A, Patniak A, Call J, Fontana E, Kotecki N, Cabanas G, Zivi A, Riess JW, Gupta S, Zhang R, Gillison M
PDL1V | PD-L1-directed Antibody Drug Conjugate | September 13, 2024 | ESMO 2024
C5851001 | NCT05208762